Centos RPM with python virtual env

I am trying to deploy my python virtualenv as centos rpm.

Following steps I have taken.

Created virtual environment with required dependencies.

One of requirement is pyOpenSSL

Built rpm package.
Now when installed on fresh centos instance, I am getting error as 'No module named OpenSSL'.

Is there any different procedure for pyOpenSSL module or do we need to install openssl-devel and openssl explicitly on new machine.

Copyright Notice：Content Author:「zoo zope」，Reproduced under the CC 4.0 BY-SA copyright license with a link to the original source and this disclaimer.
Link to original article：https://stackoverflow.com/questions/27456658/centos-rpm-with-python-virtual-env

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